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Peptide record

TPDB21184

Antibacterial Antifungal standard
52 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB21184
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 52-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
IATSPYYACNCPNNCKHKKGSGCKYHSGPSDKSKVISGKCEWQGGQLNCIAT
Physicochemical Analysis
C236H370N70O74S6
RMF
K
5564.32
8.83
9
2
12
+5
9.37
-0.731
41.35
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
10345
185.92
23
Residue Composition
number
3
A
0
R
4
N
1
D
6
C
1
E
2
Q
6
G
2
H
3
I
1
L
7
K
0
M
0
F
3
P
6
S
2
T
1
W
3
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 4 D: 1 C: 6 E: 1 Q: 2 G: 6 H: 2 I: 3 L: 1 K: 7 M: 0 F: 0 P: 3 S: 6 T: 2 W: 1 Y: 3 V: 1
Chemical Descriptors
52
C236H370N70O74S6
5564.32
8.83
+5
9.37
-0.731
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.25 µg/mL

Target

Candida albicans ATCC 10231

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against C. albicans ATCC 10231 (MIC 6.25 ug/ml), C. glabrata CBS 138 (MIC 1.56 ug/ml), C. guilliermondii CBS 566 (MIC 1.56 ug/ml), C. kru
Evidence 2 Activity

Activity

MIC
Antibacterial
1.56 µg/mL

Target

C. glabrata CBS 138

Source & Reference

dbAMP

Other

Active against C. albicans ATCC 10231 (MIC 6.25 ug/ml), C. glabrata CBS 138 (MIC 1.56 ug/ml), C. guilliermondii CBS 566 (MIC 1.56 ug/ml), C. krusei CBS 573 (MIC 12.5 ug/ml), C. lusit
Evidence 3 Activity

Activity

MIC
Antibacterial
1.56 µg/mL

Target

C. guilliermondii CBS 566

Source & Reference

dbAMP

Other

ve against C. albicans ATCC 10231 (MIC 6.25 ug/ml), C. glabrata CBS 138 (MIC 1.56 ug/ml), C. guilliermondii CBS 566 (MIC 1.56 ug/ml), C. krusei CBS 573 (MIC 12.5 ug/ml), C. lusitaniae CBS 6936 (MIC 3.1 ug/ml), C. parapsilo
Evidence 4 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

C. krusei CBS 573

Source & Reference

dbAMP

Other

ug/ml), C. glabrata CBS 138 (MIC 1.56 ug/ml), C. guilliermondii CBS 566 (MIC 1.56 ug/ml), C. krusei CBS 573 (MIC 12.5 ug/ml), C. lusitaniae CBS 6936 (MIC 3.1 ug/ml), C. parapsilosis CBS 604 (MIC 1.56 ug/ml), C. tro
Evidence 5 Activity

Activity

MIC
Antibacterial
3.1 µg/mL

Target

C. lusitaniae CBS 6936

Source & Reference

dbAMP

Other

6 ug/ml), C. guilliermondii CBS 566 (MIC 1.56 ug/ml), C. krusei CBS 573 (MIC 12.5 ug/ml), C. lusitaniae CBS 6936 (MIC 3.1 ug/ml), C. parapsilosis CBS 604 (MIC 1.56 ug/ml), C. tropicalis CBS 94 (MIC 1.56 ug/ml), S. cere
Evidence 6 Activity

Activity

MIC
Antibacterial
1.56 µg/mL

Target

C. parapsilosis CBS 604

Source & Reference

dbAMP

Other

1.56 ug/ml), C. krusei CBS 573 (MIC 12.5 ug/ml), C. lusitaniae CBS 6936 (MIC 3.1 ug/ml), C. parapsilosis CBS 604 (MIC 1.56 ug/ml), C. tropicalis CBS 94 (MIC 1.56 ug/ml), S. cerevisiae SZMC 0644 (MIC 3.1 ug/ml), and S. p
Evidence 7 Activity

Activity

MIC
Antibacterial
1.56 µg/mL

Target

C. tropicalis CBS 94

Source & Reference

dbAMP

Other

ug/ml), C. lusitaniae CBS 6936 (MIC 3.1 ug/ml), C. parapsilosis CBS 604 (MIC 1.56 ug/ml), C. tropicalis CBS 94 (MIC 1.56 ug/ml), S. cerevisiae SZMC 0644 (MIC 3.1 ug/ml), and S. pombe SZMC 0142 (MIC 1.56 ug/ml).
Evidence 8 Activity

Activity

MIC
Antibacterial
3.1 µg/mL

Target

S. cerevisiae SZMC 0644

Source & Reference

dbAMP

Other

ug/ml), C. parapsilosis CBS 604 (MIC 1.56 ug/ml), C. tropicalis CBS 94 (MIC 1.56 ug/ml), S. cerevisiae SZMC 0644 (MIC 3.1 ug/ml), and S. pombe SZMC 0142 (MIC 1.56 ug/ml).
Evidence 9 Activity

Activity

MIC
Antibacterial
1.56 µg/mL

Target

S. pombe SZMC 0142

Source & Reference

dbAMP

Other

/ml), C. tropicalis CBS 94 (MIC 1.56 ug/ml), S. cerevisiae SZMC 0644 (MIC 3.1 ug/ml), and S. pombe SZMC 0142 (MIC 1.56 ug/ml).
Evidence 10 Activity

Activity

MIC
Antifungal
6.25 µg/mL

Target

Candida albicans ATCC 10231

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against C. albicans ATCC 10231 (MIC 6.25 ug/ml), C. glabrata CBS 138 (MIC 1.56 ug/ml), C. guilliermondii CBS 566 (MIC 1.56 ug/ml), C. kru
Evidence 11 Activity

Activity

MIC
Antifungal
1.56 µg/mL

Target

C. glabrata CBS 138

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against C. albicans ATCC 10231 (MIC 6.25 ug/ml), C. glabrata CBS 138 (MIC 1.56 ug/ml), C. guilliermondii CBS 566 (MIC 1.56 ug/ml), C. krusei CBS 573 (MIC 12.5 ug/ml), C. lusit
Evidence 12 Activity

Activity

MIC
Antifungal
1.56 µg/mL

Target

C. guilliermondii CBS 566

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ve against C. albicans ATCC 10231 (MIC 6.25 ug/ml), C. glabrata CBS 138 (MIC 1.56 ug/ml), C. guilliermondii CBS 566 (MIC 1.56 ug/ml), C. krusei CBS 573 (MIC 12.5 ug/ml), C. lusitaniae CBS 6936 (MIC 3.1 ug/ml), C. parapsilo
Evidence 13 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

C. krusei CBS 573

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), C. glabrata CBS 138 (MIC 1.56 ug/ml), C. guilliermondii CBS 566 (MIC 1.56 ug/ml), C. krusei CBS 573 (MIC 12.5 ug/ml), C. lusitaniae CBS 6936 (MIC 3.1 ug/ml), C. parapsilosis CBS 604 (MIC 1.56 ug/ml), C. tro
Evidence 14 Activity

Activity

MIC
Antifungal
3.1 µg/mL

Target

C. lusitaniae CBS 6936

Source & Reference

dbAMP CAFPdb Antifungipept

Other

6 ug/ml), C. guilliermondii CBS 566 (MIC 1.56 ug/ml), C. krusei CBS 573 (MIC 12.5 ug/ml), C. lusitaniae CBS 6936 (MIC 3.1 ug/ml), C. parapsilosis CBS 604 (MIC 1.56 ug/ml), C. tropicalis CBS 94 (MIC 1.56 ug/ml), S. cere
Evidence 15 Activity

Activity

MIC
Antifungal
1.56 µg/mL

Target

C. parapsilosis CBS 604

Source & Reference

dbAMP CAFPdb Antifungipept

Other

1.56 ug/ml), C. krusei CBS 573 (MIC 12.5 ug/ml), C. lusitaniae CBS 6936 (MIC 3.1 ug/ml), C. parapsilosis CBS 604 (MIC 1.56 ug/ml), C. tropicalis CBS 94 (MIC 1.56 ug/ml), S. cerevisiae SZMC 0644 (MIC 3.1 ug/ml), and S. p
Evidence 16 Activity

Activity

MIC
Antifungal
1.56 µg/mL

Target

C. tropicalis CBS 94

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), C. lusitaniae CBS 6936 (MIC 3.1 ug/ml), C. parapsilosis CBS 604 (MIC 1.56 ug/ml), C. tropicalis CBS 94 (MIC 1.56 ug/ml), S. cerevisiae SZMC 0644 (MIC 3.1 ug/ml), and S. pombe SZMC 0142 (MIC 1.56 ug/ml).
Evidence 17 Activity

Activity

MIC
Antifungal
3.1 µg/mL

Target

S. cerevisiae SZMC 0644

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), C. parapsilosis CBS 604 (MIC 1.56 ug/ml), C. tropicalis CBS 94 (MIC 1.56 ug/ml), S. cerevisiae SZMC 0644 (MIC 3.1 ug/ml), and S. pombe SZMC 0142 (MIC 1.56 ug/ml).
Evidence 18 Activity

Activity

MIC
Antifungal
1.56 µg/mL

Target

S. pombe SZMC 0142

Source & Reference

dbAMP CAFPdb Antifungipept

Other

/ml), C. tropicalis CBS 94 (MIC 1.56 ug/ml), S. cerevisiae SZMC 0644 (MIC 3.1 ug/ml), and S. pombe SZMC 0142 (MIC 1.56 ug/ml).