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Peptide record

TPDB21139

Antibacterial Toxicity modified_plain modified
38 amino acids
Basic Information
3D PDB MODEL
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TPDB21139
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 38-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNX
Physicochemical Analysis
C197H318N60O53S1
CEPW
K
4407.12
10.72
11
2
15
+8
7.88
-0.958
61.58
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
5960
135.24
11
Residue Composition
number
3
A
4
R
1
N
2
D
0
C
0
E
2
Q
2
G
1
H
1
I
2
L
6
K
1
M
1
F
0
P
3
S
1
T
0
W
4
Y
3
V
Amino Acid Distribution
A: 3 R: 4 N: 1 D: 2 C: 0 E: 0 Q: 2 G: 2 H: 1 I: 1 L: 2 K: 6 M: 1 F: 1 P: 0 S: 3 T: 1 W: 0 Y: 4 V: 3
Chemical Descriptors
38
C197H318N60O53S1
4407.12
10.72
+8
7.88
-0.958
Evidence Records 1 records
Evidence 1 Activity

Activity

80% Hemolysis
Toxicity
30 µM
Hemolytic Cytotoxic
80% Hemolysis | 30 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Pituitary adenylate cyclase-activating polypeptide is a potent broad-spectrum antimicrobial peptide: Structure-activity relationships. | Peptides | 2018