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Peptide record

TPDB21128

Antibacterial Antiviral Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB21128
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
HRILMRIRQAMT
Physicochemical Analysis
C64H116N24O15S2
NDCEGKFPSWYV
R
1525.90
12.70
4
0
6
+3
2.30
-0.208
105.83
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
1
Q
0
G
1
H
2
I
1
L
0
K
2
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 2 L: 1 K: 0 M: 2 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C64H116N24O15S2
1525.90
12.70
+3
2.30
-0.208
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>500 µM
Cytotoxic
50% Cell death | >500 | µM | target cell: MARC-145 cells

Target

MARC-145 cells

Source & Reference

NA
DBAASP
Antiviral activity of phage display selected peptides against Porcine reproductive and respiratory syndrome virus in vitro. | Virology | 2012
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.22743126]MARC-145 cells:CC50>500 µM.

Source & Reference

NA
DRAMP
Virology. 2012 Oct 10 432(1):73-80.