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Peptide record

TPDB21127

Antibacterial Antiviral Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB21127
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
HRILMRIRAMMT
Physicochemical Analysis
C64H117N23O14S3
NDCEQGKFPSWYV
RM
1528.96
12.70
4
0
7
+3
1.49
0.242
105.83
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
2
I
1
L
0
K
3
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 2 L: 1 K: 0 M: 3 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C64H117N23O14S3
1528.96
12.70
+3
1.49
0.242
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>500 µM
Cytotoxic
50% Cell death | >500 | µM | target cell: MARC-145 cells

Target

MARC-145 cells

Source & Reference

NA
DBAASP
Antiviral activity of phage display selected peptides against Porcine reproductive and respiratory syndrome virus in vitro. | Virology | 2012
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.22743126]MARC-145 cells:CC50>500 µM.

Source & Reference

NA
DRAMP
Virology. 2012 Oct 10 432(1):73-80.