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Peptide record

TPDB21115

Antibacterial Antiviral Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB21115
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
HRIAMRIRQMMT
Physicochemical Analysis
C63H114N24O15S3
NDCEGLKFPSWYV
RM
1543.93
12.70
4
0
6
+3
2.63
-0.367
73.33
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
1
Q
0
G
1
H
2
I
0
L
0
K
3
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 2 L: 0 K: 0 M: 3 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C63H114N24O15S3
1543.93
12.70
+3
2.63
-0.367
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>500 µM
Cytotoxic
50% Cell death | >500 | µM | target cell: MARC-145 cells

Target

MARC-145 cells

Source & Reference

NA
DBAASP
Antiviral activity of phage display selected peptides against Porcine reproductive and respiratory syndrome virus in vitro. | Virology | 2012
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.22743126]MARC-145 cells:CC50>500 µM.

Source & Reference

NA
DRAMP
Virology. 2012 Oct 10 432(1):73-80.