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Peptide record

TPDB21076

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB21076
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
HLNKRVQRLLIRWLRWLK
Physicochemical Analysis
C114H190N38O21
ADCEGMFPSTY
L
2429.00
12.88
7
0
9
+6
0.44
-0.561
146.11
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
11000
452.86
2
Residue Composition
number
0
A
4
R
1
N
0
D
0
C
0
E
1
Q
0
G
1
H
1
I
5
L
2
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 1 L: 5 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
18
C114H190N38O21
2429.00
12.88
+6
0.44
-0.561
Evidence Records 1 records
Evidence 1 Activity

Activity

14% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
14% Hemolysis | 100 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Effect of alanine, leucine, and arginine substitution on antimicrobial activity against candida albicans and action mechanism of a cationic octadecapeptide derived from ?-amylase of rice. | Biopolymers | 2016