Back to search

Peptide record

TPDB21011

gH625 monomer (gH625-M) Antibacterial Antifungal Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB21011
gH625 monomer (gH625-M)
Antibacterial Antifungal Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
Peptipedia Antifungipept CAFPdb dbAMP CPPsite3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Antifungal, and Cell-penetrating Peptides) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
C-terminal: Amidation Chemical: FITC-labelled at N-terminus
Sequence
HGLASTLTRWAHYNALIRAFGGGKKKK-NH2
Physicochemical Analysis
C136H217N43O33
DCEQMPV
AGK
2982.49
11.65
8
0
11
+6
1.78
-0.541
72.59
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
6990
234.37
5
Residue Composition
number
4
A
2
R
1
N
0
D
0
C
0
E
0
Q
4
G
2
H
1
I
3
L
4
K
0
M
1
F
0
P
1
S
2
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 2 I: 1 L: 3 K: 4 M: 0 F: 1 P: 0 S: 1 T: 2 W: 1 Y: 1 V: 0
Chemical Descriptors
27
C136H217N43O33
2982.49
11.65
+6
1.78
-0.541
Amidation
FITC-labelled at N-terminus
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Persister-Derived Bioflm Of C. Albicans

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Concanavalin-A
Cytoplasm
Internalization into the cell wall at 30min, but at 180min it is essentially inside the cell.
In vitro
CCCCSSSTTSCCCGGGHHHHTSSSSCSGGGTCC
Additional Detail Fields 1 fields
CCCCSSSTTSCCCGGGHHHHTSSSSCSGGGTCC