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Peptide record

TPDB20981

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) Antibacterial Anticancer Antifungal iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB20981
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
Antibacterial Anticancer Antifungal iDPPIV
Anti-infective peptides Cardiometabolic peptides Cancer-related peptides
Peptipedia iDPPIV
standard
No
A 2-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia and iDPPIV, with an available 3D structural model.
Sequence
HA
Physicochemical Analysis
C9H14N4O3
RNDCEQGILKMFPSTWYV
AH
226.24
7.85
1
0
1
+0
0.79
-0.700
50.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C9H14N4O3
226.24
7.85
+0
0.79
-0.700
226.2319
226.1063
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Bella A. M., Erickson R. H. Jr., Kim Y. S.
Rat intestinal brush border membrane dipeptidyl-aminopeptidase IV:kinetic properties and substrate specifities of the purified enzyme.Arch. Biochem. Biophys. 218, 156-162 (1982)
1982
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CC1=CN=C[N]1[H])C(=O)N[C@@H](C)C(=O)O InChI=1S/C9H14N4O3/c1-5(9(15)16)13-8(14)7(10)2-6-3-11-4-12-6/h3-5,7H,2,10H2,1H3,(H,11,12)(H,13,14)(H,15,16)/t5-,7-/m0/s1 InChIKey: FRJIAZKQGSCKPQ-FSPLSTOPSA-N Inhibitor of Alanine carboxypeptidase (EC 3.4.17.6) (MEROPS ID: M9E.002) according to the BRENDA database
Additional Detail Fields 1 fields
2