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Peptide record

TPDB20980

Antibacterial Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB20980
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GVLVWFRRR
Physicochemical Analysis
C56H89N19O10
ANDCEQHIKMPSTY
R
1188.44
12.70
3
0
5
+3
-0.96
0.022
107.78
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
462.79
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
9
C56H89N19O10
1188.44
12.70
+3
-0.96
0.022
Evidence Records 3 records
Evidence 1 Activity

Activity

0.52 ±0.05% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
0.52 ±0.05% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 2 Activity

Activity

1.14 ±0.02% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
1.14 ±0.02% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 3 Activity

Activity

1.8±0.07% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
1.8±0.07% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022