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Peptide record

TPDB20968

Antibacterial Anticancer Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB20968
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from Peptipedia, HemoPI, Hemolytic2, and other sources, with an available 3D structural model.
Sequence
GYPICGESCVGGICNIPGCSCSWPVCTTN
Physicochemical Analysis
C121H186N32O40S6
ARDQHLKMF
C
2921.36
3.29
0
1
7
-1
-0.09
0.469
60.34
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7365
252.11
14
Residue Composition
number
0
A
0
R
2
N
0
D
6
C
1
E
0
Q
5
G
0
H
3
I
0
L
0
K
0
M
0
F
3
P
3
S
2
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 6 E: 1 Q: 0 G: 5 H: 0 I: 3 L: 0 K: 0 M: 0 F: 0 P: 3 S: 3 T: 2 W: 1 Y: 1 V: 2
Chemical Descriptors
29
C121H186N32O40S6
2921.36
3.29
-1
-0.09
0.469
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
225.90 µM
Hemolytic Cytotoxic
50% Hemolysis | 225.90 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Isolation and characterization of cytotoxic cyclotides from Viola tricolor. | Peptides | 2010
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2010 Aug 31(8):1434-40.
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis