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Peptide record

TPDB20964

Antibacterial Antiviral Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB20964
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
GYHLMSFPQAAPHGVVFLHVTW
Physicochemical Analysis
C120H168N30O27S1
RNDCEIK
HV
2494.90
8.01
3
0
12
+0
-1.88
0.477
84.09
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
280.17
4
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
1
Q
2
G
3
H
0
I
2
L
0
K
1
M
2
F
2
P
1
S
1
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 3 I: 0 L: 2 K: 0 M: 1 F: 2 P: 2 S: 1 T: 1 W: 1 Y: 1 V: 3
Chemical Descriptors
22
C120H168N30O27S1
2494.90
8.01
+0
-1.88
0.477
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Cytotoxicity
Toxicity
30 µM
Cytotoxic
0% Cytotoxicity | 30 | µM | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein. | Virus Res | 2006
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.16616792]No cytotoxicity against Vero E6 cells up to 30 µM.

Source & Reference

NA
DRAMP
Virus Res. 2006 Sep 120(1-2):146-55.