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Peptide record

TPDB20958

Antibacterial Antiviral Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB20958
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
GYFVQDDGEWKFTGSSYYY
Physicochemical Analysis
C110H138N22O34
ARNCHILMP
Y
2312.43
3.70
1
3
8
-2
-1.32
-0.932
15.26
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11460
495.58
8
Residue Composition
number
0
A
0
R
0
N
2
D
0
C
1
E
1
Q
3
G
0
H
0
I
0
L
1
K
0
M
2
F
0
P
2
S
1
T
1
W
4
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 2 C: 0 E: 1 Q: 1 G: 3 H: 0 I: 0 L: 0 K: 1 M: 0 F: 2 P: 0 S: 2 T: 1 W: 1 Y: 4 V: 1
Chemical Descriptors
19
C110H138N22O34
2312.43
3.70
-2
-1.32
-0.932
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Cytotoxicity
Toxicity
30 µM
Cytotoxic
0% Cytotoxicity | 30 | µM | target cell: Rat epithelial cells L2

Target

Rat epithelial cells L2

Source & Reference

NA
DBAASP
Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein. | Virus Res | 2006
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.16616792]No cytotoxic at a concentration of 30 µM on L2cells

Source & Reference

NA
DRAMP
Virus Res. 2006 Sep 120(1-2):146-55.
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.16616792]No cytotoxicity against Vero E6 cells up to 30 µM.

Source & Reference

NA
DRAMP
Virus Res. 2006 Sep 120(1-2):146-55.