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Peptide record

TPDB20957

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
78 amino acids
Basic Information
3D PDB MODEL
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TPDB20957
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP dbAMP 3.0 i2APP
standard
No
A 78-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
GYFCESCRKIIQKLEDMVGPQPNEDTVTQAASQVCDKLKILRGLCKKIMRSFLRRISWDILTGKKPQAICVDIKICKE
Physicochemical Analysis
C391H656N110O111S8
H
K
8930.66
9.16
15
9
28
+6
20.50
-0.231
93.72
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7365
82.47
20
Residue Composition
number
3
A
5
R
1
N
5
D
6
C
4
E
5
Q
4
G
0
H
9
I
6
L
10
K
2
M
2
F
3
P
4
S
3
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 3 R: 5 N: 1 D: 5 C: 6 E: 4 Q: 5 G: 4 H: 0 I: 9 L: 6 K: 10 M: 2 F: 2 P: 3 S: 4 T: 3 W: 1 Y: 1 V: 4
Chemical Descriptors
78
C391H656N110O111S8
8930.66
9.16
+6
20.50
-0.231
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
170 µM
Hemolytic Cytotoxic
0% Hemolysis | 170 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
NK-lysin, a novel effector peptide of cytotoxic T and NK cells. Structure and cDNA cloning of the porcine form, induction by interleukin 2, antibacterial and antitumour activity | EMBO J | 1995
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
0 %
Hemolytic Cytotoxic
Hemolytic_activity: Sheep erythrocytes: 0% Hemolysis=170 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
EMBO J. 1995 Apr 18 14(8):1615-25.