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Peptide record

TPDB20950

Antibacterial standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB20950
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 46-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GWRKRVFKPVEKFGQRVRDAGVQGIAIAQQGANVLATARGGPPQQG
Physicochemical Analysis
C216H352N72O59
CHMSY
G
4901.62
12.24
8
2
17
+6
9.78
-0.546
70.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
112.21
8
Residue Composition
number
6
A
5
R
1
N
1
D
0
C
1
E
6
Q
8
G
0
H
2
I
1
L
3
K
0
M
2
F
3
P
0
S
1
T
1
W
0
Y
5
V
Amino Acid Distribution
A: 6 R: 5 N: 1 D: 1 C: 0 E: 1 Q: 6 G: 8 H: 0 I: 2 L: 1 K: 3 M: 0 F: 2 P: 3 S: 0 T: 1 W: 1 Y: 0 V: 5
Chemical Descriptors
46
C216H352N72O59
4901.62
12.24
+6
9.78
-0.546
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.52 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against E. coli (MIC 0.52 uM),E. aerogenes (MIC 1.03 uM), and P. aeruginosa (MIC 1.03 uM). No activity was detected at
Evidence 2 Activity

Activity

MIC
Antibacterial
1.03 µM

Target

Enterobacter aerogenes

Source & Reference

NA

Other

Active against E. coli (MIC 0.52 uM),E. aerogenes (MIC 1.03 uM), and P. aeruginosa (MIC 1.03 uM). No activity was detected at 4.14 uM against Gram-positi
Evidence 3 Activity

Activity

MIC
Antibacterial
1.03 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

Active against E. coli (MIC 0.52 uM),E. aerogenes (MIC 1.03 uM), and P. aeruginosa (MIC 1.03 uM). No activity was detected at 4.14 uM against Gram-positive bacteria (MRSA, S-aureus 40881