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Peptide record

TPDB20946

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB20946
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GYCFTACYRRNGVRICYRRCN
Physicochemical Analysis
C108H168N38O28S4
DEQHLKMPSW
R
2575.00
9.60
5
0
7
+5
-0.27
-0.552
37.14
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
4720
183.30
10
Residue Composition
number
1
A
5
R
2
N
0
D
4
C
0
E
0
Q
2
G
0
H
1
I
0
L
0
K
0
M
1
F
0
P
0
S
1
T
0
W
3
Y
1
V
Amino Acid Distribution
A: 1 R: 5 N: 2 D: 0 C: 4 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 3 V: 1
Chemical Descriptors
21
C108H168N38O28S4
2575.00
9.60
+5
-0.27
-0.552
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
50% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel β-Hairpin Peptide from Marine Polychaeta with a High Efficacy against Gram-Negative Pathogens | Mar Drugs | 2022
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Novel β-Hairpin Peptide from Marine Polychaeta with a High Efficacy against Gram-Negative Pathogens | Mar Drugs | 2022