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Peptide record

TPDB20942

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB20942
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GYCFTACYLRNGVRACYRRCN
Physicochemical Analysis
C105H161N35O28S4
DEQHIKMPSW
RC
2489.89
9.14
4
0
8
+4
-1.50
-0.286
41.90
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
4720
189.57
10
Residue Composition
number
2
A
4
R
2
N
0
D
4
C
0
E
0
Q
2
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
1
T
0
W
3
Y
1
V
Amino Acid Distribution
A: 2 R: 4 N: 2 D: 0 C: 4 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 3 V: 1
Chemical Descriptors
21
C105H161N35O28S4
2489.89
9.14
+4
-1.50
-0.286
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
<10% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel β-Hairpin Peptide from Marine Polychaeta with a High Efficacy against Gram-Negative Pathogens | Mar Drugs | 2022
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Novel β-Hairpin Peptide from Marine Polychaeta with a High Efficacy against Gram-Negative Pathogens | Mar Drugs | 2022