Back to search

Peptide record

TPDB20919

Antibacterial Antifungal Toxicity modified_plain modified
19 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB20919
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 19-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
GXXQQXXXXXXQXXQXXGY
Physicochemical Analysis
C33H49N11O13
ARNDCEHILKMFPSTWV
Q
807.82
5.94
0
0
1
-0
1.40
-0.847
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
184.45
5
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
4
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 4 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
19
C33H49N11O13
807.82
5.94
-0
1.40
-0.847
Evidence Records 5 records
Evidence 1 Activity

Activity

>95% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
>95% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alpha-helical antimicrobial peptides--using a sequence template to guide structure-activity relationship studies. | Biochim Biophys Acta | 2006
Evidence 2 Activity

Activity

<5% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
<5% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alpha-helical antimicrobial peptides--using a sequence template to guide structure-activity relationship studies. | Biochim Biophys Acta | 2006
Evidence 3 Activity

Activity

10% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
10% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Amphipathic alpha helical antimicrobial peptides | Eur J Biochem | 2001
Evidence 4 Activity

Activity

60% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
60% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Amphipathic alpha helical antimicrobial peptides | Eur J Biochem | 2001
Evidence 5 Activity

Activity

25% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
25% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Amphipathic alpha helical antimicrobial peptides | Eur J Biochem | 2001