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Peptide record

TPDB20902

Antibacterial Toxicity modified_plain modified
32 amino acids
Basic Information
3D PDB MODEL
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TPDB20902
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 32-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GXRKRXRKFRNKIKEKKKKIGQKXQGLXPKLA
Physicochemical Analysis
C150H273N53O34
DCHMSTWYV
K
3363.15
12.45
14
1
6
+13
14.18
-1.644
51.88
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
4
R
1
N
0
D
0
C
1
E
2
Q
3
G
0
H
2
I
2
L
10
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 1 D: 0 C: 0 E: 1 Q: 2 G: 3 H: 0 I: 2 L: 2 K: 10 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
32
C150H273N53O34
3363.15
12.45
+13
14.18
-1.644
Evidence Records 1 records
Evidence 1 Activity

Activity

4% Hemolysis
Toxicity
25 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 25 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice. | Nat Biotechnol | 2019