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Peptide record

TPDB20895

Antibacterial Antifungal Toxicity modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB20895
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 10-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
GXLKRIKTLX
Physicochemical Analysis
C42H81N13O10
ANDCEQHMFPSWYV
LK
928.19
11.64
3
0
3
+3
1.51
-0.130
117.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
2
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C42H81N13O10
928.19
11.64
+3
1.51
-0.130
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>500 µM
Hemolytic Cytotoxic
50% Hemolysis | >500 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design of alpha-helical antimicrobial peptides: do's and don'ts. | Chembiochem | 2015
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
31.17 µM
Hemolytic Cytotoxic
50% Hemolysis | 31.17 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthetic analogs of anoplin show improved antimicrobial activities. | J Pept Sci | 2013
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
380 µM
Hemolytic Cytotoxic
50% Hemolysis | 380 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design of alpha-helical antimicrobial peptides: do's and don'ts. | Chembiochem | 2015