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Peptide record

TPDB20813

Antibacterial Antiparasitic Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB20813
Antibacterial Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Antiparasitic, and Toxicity) peptide sequence curated from Peptipedia and ToxinPred 3.0, with an available 3D structural model.
Sequence
GWKDWLNKAKDFIKEKGPEILRAAANAAIN
Physicochemical Analysis
C154H243N43O42
CQHMSTYV
A
3368.89
10.05
6
4
14
+2
6.09
-0.600
85.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
326.52
3
Residue Composition
number
6
A
1
R
3
N
2
D
0
C
2
E
0
Q
2
G
0
H
3
I
2
L
5
K
0
M
1
F
1
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 1 N: 3 D: 2 C: 0 E: 2 Q: 0 G: 2 H: 0 I: 3 L: 2 K: 5 M: 0 F: 1 P: 1 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
30
C154H243N43O42
3368.89
10.05
+2
6.09
-0.600
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities. | Biochem Pharmacol | 2021
Evidence 2 Activity

Activity

50% Cytotoxicity
Toxicity
5.2-6.8 µM
Cytotoxic
50% Cytotoxicity | 5.2-6.8 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities. | Biochem Pharmacol | 2021