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Peptide record

TPDB20793

Antibacterial standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB20793
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 32-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GWFTAVQLTLAGRCGRWFTGSYECTTNNVKCG
Physicochemical Analysis
C155H232N44O45S3
DHIMP
GT
3527.99
8.56
3
1
11
+2
-2.01
-0.112
48.75
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12615
357.57
13
Residue Composition
number
2
A
2
R
2
N
0
D
3
C
1
E
1
Q
5
G
0
H
0
I
2
L
1
K
0
M
2
F
0
P
1
S
5
T
2
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 2 D: 0 C: 3 E: 1 Q: 1 G: 5 H: 0 I: 0 L: 2 K: 1 M: 0 F: 2 P: 0 S: 1 T: 5 W: 2 Y: 1 V: 2
Chemical Descriptors
32
C155H232N44O45S3
3527.99
8.56
+2
-2.01
-0.112
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.125 µg/mL

Target

M. luteus ATCC10240

Source & Reference

NA

Other

active against Gram+ M. luteus ATCC10240 (MIC 0.125 ug/ml), S. pyogenes W51503011 or W80908630 (MIC 16 ug/ml), S. agalactiae W73106655 or W70407881
Evidence 2 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Streptococcus pyogenes W51503011 or W80908630

Source & Reference

NA

Other

active against Gram+ M. luteus ATCC10240 (MIC 0.125 ug/ml), S. pyogenes W51503011 or W80908630 (MIC 16 ug/ml), S. agalactiae W73106655 or W70407881 (MIC 16-32 ug/ml), S. pneumoniae V4122578 or W81002
Evidence 3 Activity

Activity

MIC
Antibacterial
16-32 µg/mL

Target

Streptococcus agalactiae W73106655 or W70407881

Source & Reference

NA

Other

M. luteus ATCC10240 (MIC 0.125 ug/ml), S. pyogenes W51503011 or W80908630 (MIC 16 ug/ml), S. agalactiae W73106655 or W70407881 (MIC 16-32 ug/ml), S. pneumoniae V4122578 or W81002644 (MIC 0.5-1 ug/ml), drug-resistant E. faecalis W82000
Evidence 4 Activity

Activity

MIC
Antibacterial
0.5-1 µg/mL

Target

S. pneumoniae V4122578 or W81002644

Source & Reference

NA

Other

3011 or W80908630 (MIC 16 ug/ml), S. agalactiae W73106655 or W70407881 (MIC 16-32 ug/ml), S. pneumoniae V4122578 or W81002644 (MIC 0.5-1 ug/ml), drug-resistant E. faecalis W82000259 or W80909324 or ATCC29212 (MIC 16-32 ug/ml), E. fae
Evidence 5 Activity

Activity

MIC
Antibacterial
16-32 µg/mL

Target

Enterococcus faecalis W82000259 or W80909324 or ATCC29212

Source & Reference

NA

Other

(MIC 16-32 ug/ml), S. pneumoniae V4122578 or W81002644 (MIC 0.5-1 ug/ml), drug-resistant E. faecalis W82000259 or W80909324 or ATCC29212 (MIC 16-32 ug/ml), E. faecium W97542221 (MIC 64 ug/ml) anti-VRE, L-rhamnosus ATCC11981 (MIC>64 ug/ml), S-mu
Evidence 6 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

E. faecium W97542221

Source & Reference

NA

Other

ug/ml), drug-resistant E. faecalis W82000259 or W80909324 or ATCC29212 (MIC 16-32 ug/ml), E. faecium W97542221 (MIC 64 ug/ml) anti-VRE, L-rhamnosus ATCC11981 (MIC>64 ug/ml), S-mutans UA159 (MIC > 64 ug/ml), Gram- N.
Evidence 7 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

N. gonorrhoeae V3091967

Source & Reference

NA

Other

l) anti-VRE, L-rhamnosus ATCC11981 (MIC>64 ug/ml), S-mutans UA159 (MIC > 64 ug/ml), Gram- N. gonorrhoeae V3091967 (MIC 64 ug/ml), P. gingivalis ATCC33277 (MIC 32 ug/ml), and T. forsythia ATCC43037 (MIC 32 ug/ml). Prima
Evidence 8 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

P. gingivalis ATCC33277

Source & Reference

NA

Other

64 ug/ml), S-mutans UA159 (MIC > 64 ug/ml), Gram- N. gonorrhoeae V3091967 (MIC 64 ug/ml), P. gingivalis ATCC33277 (MIC 32 ug/ml), and T. forsythia ATCC43037 (MIC 32 ug/ml). Primarily kill oral pathogens in a selective
Evidence 9 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

T. forsythia ATCC43037

Source & Reference

NA

Other

Gram- N. gonorrhoeae V3091967 (MIC 64 ug/ml), P. gingivalis ATCC33277 (MIC 32 ug/ml), and T. forsythia ATCC43037 (MIC 32 ug/ml). Primarily kill oral pathogens in a selective manner.