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Peptide record

TPDB20791

Antibacterial Anticancer Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB20791
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GWFSLVRKVVGGVGSL
Physicochemical Analysis
C78H125N21O19
ANDCEQHIMPTY
GV
1660.98
11.49
2
0
8
+2
-1.72
0.919
121.25
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
331.13
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
2
L
1
K
0
M
1
F
0
P
2
S
0
T
1
W
0
Y
4
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 2 K: 1 M: 0 F: 1 P: 0 S: 2 T: 0 W: 1 Y: 0 V: 4
Chemical Descriptors
16
C78H125N21O19
1660.98
11.49
+2
-1.72
0.919
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

E. coli ATCC 25922 (MBC 17.5 uM), P. aeruginosa (MBC 35 uM), S. aureus ATCC 29213 (MBC 40 uM), E-faecalis ATCC 29212 (MBC >70 uM), B. cereus ATCC 6464 (MBC 70 uM).
Evidence 2 Activity

Activity

10% Cell death
Toxicity
50 µM
Cytotoxic
10% Cell death | 50 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Ramosin: The First Antibacterial Peptide Identified on Bolitoglossa ramosi Colombian Salamander. | Pharmaceutics | 2022
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ramosin: The First Antibacterial Peptide Identified on Bolitoglossa ramosi Colombian Salamander. | Pharmaceutics | 2022