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Peptide record

TPDB20790

Antibacterial Antifungal standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB20790
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse
standard
No
A 37-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and AFP-GFuse, with an available 3D structural model.
Sequence
GWFKKTVKKVGGWYNKHKPTIHKVGGAVWNVVKKWKK
Physicochemical Analysis
C210H324N58O43
RDCEQLMS
K
4349.25
11.18
13
0
14
+11
4.90
-0.862
60.27
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
23490
540.09
5
Residue Composition
number
1
A
0
R
2
N
0
D
0
C
0
E
0
Q
5
G
2
H
1
I
0
L
11
K
0
M
1
F
1
P
0
S
2
T
4
W
1
Y
6
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 2 I: 1 L: 0 K: 11 M: 0 F: 1 P: 1 S: 0 T: 2 W: 4 Y: 1 V: 6
Chemical Descriptors
37
C210H324N58O43
4349.25
11.18
+11
4.90
-0.862
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3.1 µg/mL

Target

B. clausii

Source & Reference

NA

Other

Active against B. clausii (MIC 3.1 ug/ml), S. epidermidis ATCC 700565 (MIC 3.1 ug/ml), E. coli O4 (MIC 50 ug/ml), P. mirabilis ATCC
Evidence 2 Activity

Activity

MIC
Antibacterial
3.1 µg/mL

Target

Staphylococcus epidermidis ATCC 700565

Source & Reference

NA

Other

Active against B. clausii (MIC 3.1 ug/ml), S. epidermidis ATCC 700565 (MIC 3.1 ug/ml), E. coli O4 (MIC 50 ug/ml), P. mirabilis ATCC 29906 (MIC 6.3 ug/ml), and S. cerevisiae (M
Evidence 3 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

Escherichia coli O4

Source & Reference

NA

Other

Active against B. clausii (MIC 3.1 ug/ml), S. epidermidis ATCC 700565 (MIC 3.1 ug/ml), E. coli O4 (MIC 50 ug/ml), P. mirabilis ATCC 29906 (MIC 6.3 ug/ml), and S. cerevisiae (MIC 6.3 ug/ml). Lower MBC of
Evidence 4 Activity

Activity

MIC
Antibacterial
6.3 µg/mL

Target

P. mirabilis ATCC 29906

Source & Reference

NA

Other

i (MIC 3.1 ug/ml), S. epidermidis ATCC 700565 (MIC 3.1 ug/ml), E. coli O4 (MIC 50 ug/ml), P. mirabilis ATCC 29906 (MIC 6.3 ug/ml), and S. cerevisiae (MIC 6.3 ug/ml). Lower MBC of 12.5 ug/ml was found for S. epidermidis
Evidence 5 Activity

Activity

MIC
Antibacterial
6.3 µg/mL

Target

S. cerevisiae

Source & Reference

NA

Other

(MIC 3.1 ug/ml), E. coli O4 (MIC 50 ug/ml), P. mirabilis ATCC 29906 (MIC 6.3 ug/ml), and S. cerevisiae (MIC 6.3 ug/ml). Lower MBC of 12.5 ug/ml was found for S. epidermidis and S. cerevisiae, indicating a bac
Evidence 6 Activity

Activity

MIC
Antifungal
3.1 µg/mL

Target

B. clausii

Source & Reference

NA

Other

Active against B. clausii (MIC 3.1 ug/ml), S. epidermidis ATCC 700565 (MIC 3.1 ug/ml), E. coli O4 (MIC 50 ug/ml), P. mirabilis ATCC
Evidence 7 Activity

Activity

MIC
Antifungal
3.1 µg/mL

Target

Staphylococcus epidermidis ATCC 700565

Source & Reference

NA

Other

Active against B. clausii (MIC 3.1 ug/ml), S. epidermidis ATCC 700565 (MIC 3.1 ug/ml), E. coli O4 (MIC 50 ug/ml), P. mirabilis ATCC 29906 (MIC 6.3 ug/ml), and S. cerevisiae (M
Evidence 8 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

Escherichia coli O4

Source & Reference

NA

Other

Active against B. clausii (MIC 3.1 ug/ml), S. epidermidis ATCC 700565 (MIC 3.1 ug/ml), E. coli O4 (MIC 50 ug/ml), P. mirabilis ATCC 29906 (MIC 6.3 ug/ml), and S. cerevisiae (MIC 6.3 ug/ml). Lower MBC of
Evidence 9 Activity

Activity

MIC
Antifungal
6.3 µg/mL

Target

P. mirabilis ATCC 29906

Source & Reference

NA

Other

i (MIC 3.1 ug/ml), S. epidermidis ATCC 700565 (MIC 3.1 ug/ml), E. coli O4 (MIC 50 ug/ml), P. mirabilis ATCC 29906 (MIC 6.3 ug/ml), and S. cerevisiae (MIC 6.3 ug/ml). Lower MBC of 12.5 ug/ml was found for S. epidermidis
Evidence 10 Activity

Activity

MIC
Antifungal
6.3 µg/mL

Target

S. cerevisiae

Source & Reference

NA

Other

(MIC 3.1 ug/ml), E. coli O4 (MIC 50 ug/ml), P. mirabilis ATCC 29906 (MIC 6.3 ug/ml), and S. cerevisiae (MIC 6.3 ug/ml). Lower MBC of 12.5 ug/ml was found for S. epidermidis and S. cerevisiae, indicating a bac