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Peptide record

TPDB20752

Anti-inflammatory Antibacterial standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB20752
Anti-inflammatory Antibacterial
Anti-infective peptides Immunity and inflammation peptides
Peptipedia
standard
No
A 27-aa standard natural multi-activity (Anti-inflammatory and Antibacterial) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GVFYPWRFRLLCLLRRWLPRPRAWFIR
Physicochemical Analysis
C175H261N51O29S1
NDEQHKMST
R
3575.38
12.53
7
0
15
+7
-6.30
-0.011
101.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
17990
503.16
2
Residue Composition
number
1
A
7
R
0
N
0
D
1
C
0
E
0
Q
1
G
0
H
1
I
5
L
0
K
0
M
3
F
3
P
0
S
0
T
3
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 7 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 5 K: 0 M: 0 F: 3 P: 3 S: 0 T: 0 W: 3 Y: 1 V: 1
Chemical Descriptors
27
C175H261N51O29S1
3575.38
12.53
+7
-6.30
-0.011
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5 µM

Target

Staphylococcus aureus ATCC 29213 or MRSA WKZ-2

Source & Reference

NA

Other

Antimicrobial: active against Gram+ S. aureus ATCC 29213 or MRSA WKZ-2 (MIC 5 uM), B. globigii TNO BMO13 (MIC 5 uM), Gram- E. coli ATCC 25922 (MIC 10 uM), P. aeruginosa AT
Evidence 2 Activity

Activity

MIC
Antibacterial
5 µM

Target

B. globigii TNO BMO13

Source & Reference

NA

Other

Antimicrobial: active against Gram+ S. aureus ATCC 29213 or MRSA WKZ-2 (MIC 5 uM), B. globigii TNO BMO13 (MIC 5 uM), Gram- E. coli ATCC 25922 (MIC 10 uM), P. aeruginosa ATCC 27853 (MIC 10 uM) P. aeruginos
Evidence 3 Activity

Activity

MIC
Antibacterial
10 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

m+ S. aureus ATCC 29213 or MRSA WKZ-2 (MIC 5 uM), B. globigii TNO BMO13 (MIC 5 uM), Gram- E. coli ATCC 25922 (MIC 10 uM), P. aeruginosa ATCC 27853 (MIC 10 uM) P. aeruginosa PAO1 (MIC 20 uM), and S. enteriditis
Evidence 4 Activity

Activity

MIC
Antibacterial
10 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

NA

Other

WKZ-2 (MIC 5 uM), B. globigii TNO BMO13 (MIC 5 uM), Gram- E. coli ATCC 25922 (MIC 10 uM), P. aeruginosa ATCC 27853 (MIC 10 uM) P. aeruginosa PAO1 (MIC 20 uM), and S. enteriditis 706 RIVM (MIC 10 uM). Anti-inflammato
Evidence 5 Activity

Activity

MIC
Antibacterial
20 µM

Target

Pseudomonas aeruginosa PAO1

Source & Reference

NA

Other

3 (MIC 5 uM), Gram- E. coli ATCC 25922 (MIC 10 uM), P. aeruginosa ATCC 27853 (MIC 10 uM) P. aeruginosa PAO1 (MIC 20 uM), and S. enteriditis 706 RIVM (MIC 10 uM). Anti-inflammatory: 5 or 20 uM peptide reduced t
Evidence 6 Activity

Activity

MIC
Antibacterial
10 µM

Target

S. enteriditis 706 RIVM

Source & Reference

NA

Other

22 (MIC 10 uM), P. aeruginosa ATCC 27853 (MIC 10 uM) P. aeruginosa PAO1 (MIC 20 uM), and S. enteriditis 706 RIVM (MIC 10 uM). Anti-inflammatory: 5 or 20 uM peptide reduced the production of NO and IL-6 induced by 5