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Peptide record

TPDB20750

Antibacterial Antifungal Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB20750
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and ToxinPred 3.0, with an available 3D structural model.
Sequence
GVFKDALKQLGAALLDKAANALKPK
Physicochemical Analysis
C118H202N32O32
RCEHIMSTWY
A
2581.10
10.38
5
2
13
+3
4.00
0.036
113.60
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
6
A
0
R
1
N
2
D
0
C
0
E
1
Q
2
G
0
H
0
I
5
L
5
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 6 R: 0 N: 1 D: 2 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 5 K: 5 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
25
C118H202N32O32
2581.10
10.38
+3
4.00
0.036
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
24.8 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 24.8 uM), Gram+ S.aureus ATCC 29213 (MIC 198.37 uM), and fungus C.albicans ATCC 10231 (MIC >198.37
Evidence 2 Activity

Activity

MIC
Antibacterial
198.37 µM

Target

S.aureus ATCC 29213

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 24.8 uM), Gram+ S.aureus ATCC 29213 (MIC 198.37 uM), and fungus C.albicans ATCC 10231 (MIC >198.37 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
>198.37 µM

Target

C.albicans ATCC 10231

Source & Reference

NA

Other

- E. coli ATCC 25922 (MIC 24.8 uM), Gram+ S.aureus ATCC 29213 (MIC 198.37 uM), and fungus C.albicans ATCC 10231 (MIC >198.37 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
24.8 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 24.8 uM), Gram+ S.aureus ATCC 29213 (MIC 198.37 uM), and fungus C.albicans ATCC 10231 (MIC >198.37
Evidence 5 Activity

Activity

MIC
Antifungal
198.37 µM

Target

S.aureus ATCC 29213

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 24.8 uM), Gram+ S.aureus ATCC 29213 (MIC 198.37 uM), and fungus C.albicans ATCC 10231 (MIC >198.37 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
>198.37 µM

Target

C.albicans ATCC 10231

Source & Reference

NA

Other

- E. coli ATCC 25922 (MIC 24.8 uM), Gram+ S.aureus ATCC 29213 (MIC 198.37 uM), and fungus C.albicans ATCC 10231 (MIC >198.37 uM).
Evidence 7 Activity

Activity

8.8% Hemolysis
Toxicity
198.37 µM
Hemolytic Cytotoxic
8.8% Hemolysis | 198.37 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Picturins and Pictuseptins, two novel antimicrobial peptide families from the skin secretions of the Chachi treefrog, Boana picturata. | J Proteomics | 2022