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Peptide record

TPDB20749

Antibacterial Antifungal Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB20749
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and ToxinPred 3.0, with an available 3D structural model.
Sequence
GVFKDALKQFGAALLDQAANALKPK
Physicochemical Analysis
C120H196N32O33
RCEHIMSTWY
A
2615.07
10.16
4
2
13
+2
3.02
0.012
98.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
6
A
0
R
1
N
2
D
0
C
0
E
2
Q
2
G
0
H
0
I
4
L
4
K
0
M
2
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 6 R: 0 N: 1 D: 2 C: 0 E: 0 Q: 2 G: 2 H: 0 I: 0 L: 4 K: 4 M: 0 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
25
C120H196N32O33
2615.07
10.16
+2
3.02
0.012
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
48.98 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 48.98 uM), Gram+ S. aureus ATCC 29213 (MIC 97.95 uM), and fungus C.albicans ATCC 10231 (MIC 195.91
Evidence 2 Activity

Activity

MIC
Antibacterial
97.95 µM

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 48.98 uM), Gram+ S. aureus ATCC 29213 (MIC 97.95 uM), and fungus C.albicans ATCC 10231 (MIC 195.91 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
195.91 µM

Target

C.albicans ATCC 10231

Source & Reference

NA

Other

E. coli ATCC 25922 (MIC 48.98 uM), Gram+ S. aureus ATCC 29213 (MIC 97.95 uM), and fungus C.albicans ATCC 10231 (MIC 195.91 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
48.98 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 48.98 uM), Gram+ S. aureus ATCC 29213 (MIC 97.95 uM), and fungus C.albicans ATCC 10231 (MIC 195.91
Evidence 5 Activity

Activity

MIC
Antifungal
97.95 µM

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 48.98 uM), Gram+ S. aureus ATCC 29213 (MIC 97.95 uM), and fungus C.albicans ATCC 10231 (MIC 195.91 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
195.91 µM

Target

C.albicans ATCC 10231

Source & Reference

NA

Other

E. coli ATCC 25922 (MIC 48.98 uM), Gram+ S. aureus ATCC 29213 (MIC 97.95 uM), and fungus C.albicans ATCC 10231 (MIC 195.91 uM).
Evidence 7 Activity

Activity

88.1% Hemolysis
Toxicity
195.91 µM
Hemolytic Cytotoxic
88.1% Hemolysis | 195.91 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Picturins and Pictuseptins, two novel antimicrobial peptide families from the skin secretions of the Chachi treefrog, Boana picturata. | J Proteomics | 2022
Evidence 8 Activity

Activity

28.3% Hemolysis
Toxicity
97.95 µM
Hemolytic Cytotoxic
28.3% Hemolysis | 97.95 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Picturins and Pictuseptins, two novel antimicrobial peptide families from the skin secretions of the Chachi treefrog, Boana picturata. | J Proteomics | 2022