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Peptide record

TPDB20748

Antibacterial Antifungal Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB20748
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and ToxinPred 3.0, with an available 3D structural model.
Sequence
GVFKDALKQFGAALLDKAANALKPK
Physicochemical Analysis
C121H200N32O32
RCEHIMSTWY
A
2615.11
10.38
5
2
13
+3
3.43
-0.004
98.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
6
A
0
R
1
N
2
D
0
C
0
E
1
Q
2
G
0
H
0
I
4
L
5
K
0
M
2
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 6 R: 0 N: 1 D: 2 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 4 K: 5 M: 0 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
25
C121H200N32O32
2615.11
10.38
+3
3.43
-0.004
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
48.95 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 48.95 uM), Gram+ S.aureus ATCC 29213 (MIC >195.8 uM), and fungus C.albicans ATCC 10231 (MIC >195.8
Evidence 2 Activity

Activity

MIC
Antibacterial
>195.8 µM

Target

S.aureus ATCC 29213

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 48.95 uM), Gram+ S.aureus ATCC 29213 (MIC >195.8 uM), and fungus C.albicans ATCC 10231 (MIC >195.8 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
>195.8 µM

Target

C.albicans ATCC 10231

Source & Reference

NA

Other

E. coli ATCC 25922 (MIC 48.95 uM), Gram+ S.aureus ATCC 29213 (MIC >195.8 uM), and fungus C.albicans ATCC 10231 (MIC >195.8 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
48.95 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 48.95 uM), Gram+ S.aureus ATCC 29213 (MIC >195.8 uM), and fungus C.albicans ATCC 10231 (MIC >195.8
Evidence 5 Activity

Activity

MIC
Antifungal
>195.8 µM

Target

S.aureus ATCC 29213

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 48.95 uM), Gram+ S.aureus ATCC 29213 (MIC >195.8 uM), and fungus C.albicans ATCC 10231 (MIC >195.8 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
>195.8 µM

Target

C.albicans ATCC 10231

Source & Reference

NA

Other

E. coli ATCC 25922 (MIC 48.95 uM), Gram+ S.aureus ATCC 29213 (MIC >195.8 uM), and fungus C.albicans ATCC 10231 (MIC >195.8 uM).
Evidence 7 Activity

Activity

4.5% Hemolysis
Toxicity
195.79 µM
Hemolytic Cytotoxic
4.5% Hemolysis | 195.79 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Picturins and Pictuseptins, two novel antimicrobial peptide families from the skin secretions of the Chachi treefrog, Boana picturata. | J Proteomics | 2022