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Peptide record

TPDB20745

Antibacterial Antifungal Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB20745
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
GVIKAAKKVVKVLKNLF
Physicochemical Analysis
C89H159N23O19
RDCEQHMPSTWY
K
1855.38
11.12
5
0
10
+5
2.76
0.700
148.82
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
17
C89H159N23O19
1855.38
11.12
+5
2.76
0.700
Evidence Records 4 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 3 Activity

Activity

IC50
Toxicity
8.67±2.21 µg/mL
Cytotoxic
IC50 | 8.67±2.21 | µg/mL | target cell: Human vaginal epithelial cells VK2/E6E7

Target

Human vaginal epithelial cells VK2/E6E7

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 4 Activity

Activity

IC50
Toxicity
9.73±1.19 µg/mL
Cytotoxic
IC50 | 9.73±1.19 | µg/mL | target cell: Human esophagus epithelial cells Het-1A

Target

Human esophagus epithelial cells Het-1A

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015