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Peptide record

TPDB20690

Antibacterial Anticancer Antifungal Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB20690
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CAFPdb
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Sequence
GSTLLSLL
Physicochemical Analysis
C36H66N8O12
ARNDCEQHIKMFPWYV
L
802.97
6.02
0
0
4
-0
-1.83
1.562
195.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
4
L
0
K
0
M
0
F
0
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 4 K: 0 M: 0 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C36H66N8O12
802.97
6.02
-0
-1.83
1.562
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
260 µM
Cytotoxic
50% Cell death | 260 | µM | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Lipopeptide biosurfactant pseudofactin II induced apoptosis of melanoma A 375 cells by specific interaction with the plasma membrane. | PLoS One | 2013
Evidence 2 Activity

Activity

50% Cell death
Toxicity
260 µM
Cytotoxic
50% Cell death | 260 | µM | target cell: Human Primary Epidermal Keratinocytes (HEK)

Target

Human Primary Epidermal Keratinocytes (HEK)

Source & Reference

NA
DBAASP
Lipopeptide biosurfactant pseudofactin II induced apoptosis of melanoma A 375 cells by specific interaction with the plasma membrane. | PLoS One | 2013
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Colloids Surf B Biointerfaces. 2016 Oct 1 146:498-506.