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Peptide record

TPDB20670

Antibacterial Antifungal Toxicity standard
55 amino acids
Basic Information
3D PDB MODEL
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TPDB20670
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 55-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
GSKRWRKFEKKVKKALEDAKEKLQEERVQKIVEHTKEALPVIKAVATVVGVVGRR
Physicochemical Analysis
C283H486N86O77
NCMY
K
6325.50
10.74
17
8
21
+8
27.82
-0.718
92.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
86.95
5
Residue Composition
number
5
A
5
R
0
N
1
D
0
C
7
E
2
Q
3
G
1
H
2
I
3
L
11
K
0
M
1
F
1
P
1
S
2
T
1
W
0
Y
9
V
Amino Acid Distribution
A: 5 R: 5 N: 0 D: 1 C: 0 E: 7 Q: 2 G: 3 H: 1 I: 2 L: 3 K: 11 M: 0 F: 1 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 9
Chemical Descriptors
55
C283H486N86O77
6325.50
10.74
+8
27.82
-0.718
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 50 uM), K. pneumoniae ATCC BAA 1705 (MIC 25 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
25 µM

Target

Klebsiella pneumoniae ATCC BAA 1705

Source & Reference

dbAMP

Other

Active against E. coli (MIC 50 uM), K. pneumoniae ATCC BAA 1705 (MIC 25 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
50 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 50 uM), K. pneumoniae ATCC BAA 1705 (MIC 25 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
25 µM

Target

Klebsiella pneumoniae ATCC BAA 1705

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 50 uM), K. pneumoniae ATCC BAA 1705 (MIC 25 uM).
Evidence 5 Activity

Activity

0% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle. | PLoS One | 2017
Evidence 6 Activity

Activity

20% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle. | PLoS One | 2017
Evidence 7 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle. | PLoS One | 2017