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Peptide record

TPDB20669

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB20669
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GSKKPVPIIYTNRRTGKCQRM
Physicochemical Analysis
C104H181N35O28S2
ADEHLFW
RK
2433.92
11.49
6
0
5
+6
5.77
-1.052
50.95
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
61.22
7
Residue Composition
number
0
A
3
R
1
N
0
D
1
C
0
E
1
Q
2
G
0
H
2
I
0
L
3
K
1
M
0
F
2
P
1
S
2
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 1 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 0 K: 3 M: 1 F: 0 P: 2 S: 1 T: 2 W: 0 Y: 1 V: 1
Chemical Descriptors
21
C104H181N35O28S2
2433.92
11.49
+6
5.77
-1.052
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Semisynthetic Macrocyclic Lipo-lanthipeptides Display Antimicrobial Activity Against Bacterial Pathogens. | ACS Synth Biol | 2021
Evidence 2 Activity

Activity

1.3±0.3% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
1.3±0.3% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Semisynthetic Macrocyclic Lipo-lanthipeptides Display Antimicrobial Activity Against Bacterial Pathogens. | ACS Synth Biol | 2021