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Peptide record

TPDB20661

Antibacterial standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB20661
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 21-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GSKKPVPIIACNRRTGKCQRA
Physicochemical Analysis
C95H171N35O26S2
DEHLMFWY
RK
2283.74
11.46
6
0
5
+6
6.22
-0.757
60.48
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
5.47
6
Residue Composition
number
2
A
3
R
1
N
0
D
2
C
0
E
1
Q
2
G
0
H
2
I
0
L
3
K
0
M
0
F
2
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 3 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 0 K: 3 M: 0 F: 0 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
21
C95H171N35O26S2
2283.74
11.46
+6
6.22
-0.757
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6 µM

Target

Escherichia coli BL21

Source & Reference

NA

Other

active against E. coli BL21 (MIC 6 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. enterica ATCC 14028 (MIC 4 uM), K. pneumoniae AT
Evidence 2 Activity

Activity

MIC
Antibacterial
4 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

NA

Other

active against E. coli BL21 (MIC 6 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. enterica ATCC 14028 (MIC 4 uM), K. pneumoniae ATCC 13883 (2 uM), S. aureus ATCC 25923
Evidence 3 Activity

Activity

MIC
Antibacterial
4 µM

Target

S. enterica ATCC 14028

Source & Reference

NA

Other

active against E. coli BL21 (MIC 6 uM), P. aeruginosa ATCC 27853 (MIC 4 uM), S. enterica ATCC 14028 (MIC 4 uM), K. pneumoniae ATCC 13883 (2 uM), S. aureus ATCC 25923 (MIC 4 uM), B. subtilis (MIC 8 uM)
Evidence 4 Activity

Activity

MIC
Antibacterial
4 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

TCC 27853 (MIC 4 uM), S. enterica ATCC 14028 (MIC 4 uM), K. pneumoniae ATCC 13883 (2 uM), S. aureus ATCC 25923 (MIC 4 uM), B. subtilis (MIC 8 uM), S. pyogenes ATCC 19615 (MIC 6 uM), E. faecalis ATCC 29212 (MIC 2
Evidence 5 Activity

Activity

MIC
Antibacterial
8 µM

Target

B. subtilis

Source & Reference

NA

Other

ATCC 14028 (MIC 4 uM), K. pneumoniae ATCC 13883 (2 uM), S. aureus ATCC 25923 (MIC 4 uM), B. subtilis (MIC 8 uM), S. pyogenes ATCC 19615 (MIC 6 uM), E. faecalis ATCC 29212 (MIC 2 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
6 µM

Target

Streptococcus pyogenes ATCC 19615

Source & Reference

NA

Other

K. pneumoniae ATCC 13883 (2 uM), S. aureus ATCC 25923 (MIC 4 uM), B. subtilis (MIC 8 uM), S. pyogenes ATCC 19615 (MIC 6 uM), E. faecalis ATCC 29212 (MIC 2 uM).
Evidence 7 Activity

Activity

MIC
Antibacterial
2 µM

Target

Enterococcus faecalis ATCC 29212

Source & Reference

NA

Other

aureus ATCC 25923 (MIC 4 uM), B. subtilis (MIC 8 uM), S. pyogenes ATCC 19615 (MIC 6 uM), E. faecalis ATCC 29212 (MIC 2 uM).