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Peptide record

TPDB20636

Antibacterial Anticancer Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB20636
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GRLIDKIARKLVKKIQRFARKFF
Physicochemical Analysis
C133H227N41O27
NCEHMPSTWY
K
2832.52
12.43
9
1
11
+8
4.30
-0.330
106.09
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
4
R
0
N
1
D
0
C
0
E
1
Q
1
G
0
H
3
I
2
L
5
K
0
M
3
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 3 L: 2 K: 5 M: 0 F: 3 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C133H227N41O27
2832.52
12.43
+8
4.30
-0.330
Evidence Records 5 records
Evidence 1 Activity

Activity

3.5% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
3.5% Hemolysis | 5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
SAMA peptide, a rationally designed antimicrobial peptide | J App Pharm Sci | 2022
Evidence 2 Activity

Activity

7.3% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
7.3% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
SAMA peptide, a rationally designed antimicrobial peptide | J App Pharm Sci | 2022
Evidence 3 Activity

Activity

20.1% Hemolysis
Toxicity
18 µM
Hemolytic Cytotoxic
20.1% Hemolysis | 18 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
SAMA peptide, a rationally designed antimicrobial peptide | J App Pharm Sci | 2022
Evidence 4 Activity

Activity

34.2% Hemolysis
Toxicity
65 µM
Hemolytic Cytotoxic
34.2% Hemolysis | 65 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
SAMA peptide, a rationally designed antimicrobial peptide | J App Pharm Sci | 2022
Evidence 5 Activity

Activity

39.2% Hemolysis
Toxicity
124 µM
Hemolytic Cytotoxic
39.2% Hemolysis | 124 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
SAMA peptide, a rationally designed antimicrobial peptide | J App Pharm Sci | 2022