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Peptide record

TPDB20593

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB20593
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Sequence
GRHGSGLGHSSSHGQHGSGSGR
Physicochemical Analysis
C81H127N37O30
ANDCEIKMFPTWYV
G
2099.13
12.40
6
0
1
+2
6.34
-1.341
17.73
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
1
Q
8
G
4
H
0
I
1
L
0
K
0
M
0
F
0
P
6
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 8 H: 4 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 6 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
22
C81H127N37O30
2099.13
12.40
+2
6.34
-1.341
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>32 µg/mL
Cytotoxic
50% Cytotoxicity | >32 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives. | Sci Rep | 2019