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Peptide record

TPDB20584

Antibacterial Antifungal Toxicity modified_plain modified
26 amino acids
Basic Information
3D PDB MODEL
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TPDB20584
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
modified_plain
Yes
A 26-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
GQHGSSSGHSSTHGQHGSASGQSSSX
Physicochemical Analysis
C88H134N36O40
RNDCEILKMFPWYV
S
2336.25
8.15
4
0
1
+0
6.91
-1.254
3.85
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
14
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
3
Q
6
G
4
H
0
I
0
L
0
K
0
M
0
F
0
P
10
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 3 G: 6 H: 4 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 10 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
26
C88H134N36O40
2336.25
8.15
+0
6.91
-1.254
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
22.6-28.6 µg/mL
Cytotoxic
50% Cytotoxicity | 22.6-28.6 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives. | Sci Rep | 2019