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Peptide record

TPDB20583

Antibacterial Antiviral Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB20583
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
GQGKAHNGRLITANP
Physicochemical Analysis
C64H108N24O20
DCEMFSWYV
G
1533.71
11.49
3
0
4
+2
3.59
-0.913
65.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
2
A
1
R
2
N
0
D
0
C
0
E
1
Q
3
G
1
H
1
I
1
L
1
K
0
M
0
F
1
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 1 I: 1 L: 1 K: 1 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C64H108N24O20
1533.71
11.49
+2
3.59
-0.913
Evidence Records 3 records
Evidence 1 Activity

Activity

12% Cell death
Toxicity
50 µM
Cytotoxic
12% Cell death | 50 | µM | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
In vitro analysis of synthetic peptides in blocking the entry of dengue virus. | Virus Res | 2019
Evidence 2 Activity

Activity

20% Cell death
Toxicity
200 µM
Cytotoxic
20% Cell death | 200 | µM | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
In vitro analysis of synthetic peptides in blocking the entry of dengue virus. | Virus Res | 2019
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.30508603]<20% cytotoxicity against Vero and C6/36 cells at 200 µM.

Source & Reference

NA
DRAMP
Virus Res. 2019 Jan 15 260:142-150.