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Peptide record

TPDB20578

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
74 amino acids
Basic Information
3D PDB MODEL
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TPDB20578
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia dbACP Antifungipept CAFPdb dbAMP dbAMP 3.0
standard
No
A 74-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, dbACP, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLR
Physicochemical Analysis
C362H612N126O108S6
H
R
8649.98
11.22
17
6
23
+11
20.43
-0.818
64.46
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
8730
100.93
25
Residue Composition
number
4
A
13
R
2
N
4
D
4
C
2
E
6
Q
4
G
0
H
2
I
4
L
4
K
2
M
1
F
1
P
4
S
7
T
1
W
2
Y
7
V
Amino Acid Distribution
A: 4 R: 13 N: 2 D: 4 C: 4 E: 2 Q: 6 G: 4 H: 0 I: 2 L: 4 K: 4 M: 2 F: 1 P: 1 S: 4 T: 7 W: 1 Y: 2 V: 7
Chemical Descriptors
74
C362H612N126O108S6
8649.98
11.22
+11
20.43
-0.818
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
(see the ref), a recombinant peptide showed activity in vitro against bacteria (S. typhimurium, L. monocytogenes, E. coli, and S. aureus), fungi C. neoformans, C. albicans, and parasites L. major.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
(see the ref), a recombinant peptide showed activity in vitro against bacteria (S. typhimurium, L. monocytogenes, E. coli, and S. aureus), fungi C. neoformans, C. albicans, and parasites L. major.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
(see the ref), a recombinant peptide showed activity in vitro against bacteria (S. typhimurium, L. monocytogenes, E. coli, and S. aureus), fungi C. neoformans, C. albicans, and parasites L. major.