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Peptide record

TPDB20576

Antibacterial Antifungal standard
102 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB20576
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 102-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
GQALNKLMPKIVSAIIYMVGQPNAGVTFLGHQCLVESTRQPDGFYTAKMSCASWTHDNPIVGEGRSRVELEALKGSITNFVQTASNYKKFTIDEVEDWIASY
Physicochemical Analysis
C502H781N133O152S5
AGSV
11271.82
6.09
11
10
42
-1
16.75
-0.167
80.29
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
17085
151.57
31
Residue Composition
number
8
A
3
R
5
N
4
D
2
C
6
E
5
Q
8
G
2
H
7
I
6
L
6
K
3
M
4
F
4
P
8
S
7
T
2
W
4
Y
8
V
Amino Acid Distribution
A: 8 R: 3 N: 5 D: 4 C: 2 E: 6 Q: 5 G: 8 H: 2 I: 7 L: 6 K: 6 M: 3 F: 4 P: 4 S: 8 T: 7 W: 2 Y: 4 V: 8
Chemical Descriptors
102
C502H781N133O152S5
11271.82
6.09
-1
16.75
-0.167
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
30-60 µM

Target

A. hydrophila

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
binant protein, in vitro activity assays revealed that it is active against Gram-negative A. hydrophila (MIC 30-60 uM), P. fluorescens (MIC 12.5-25 uM), S. flexneri (MIC 25-50 uM), E-coli (MIC >50 uM), V-harv
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5-25 µM

Target

Pseudomonas fluorescens

Source & Reference

dbAMP

Other

ity assays revealed that it is active against Gram-negative A. hydrophila (MIC 30-60 uM), P. fluorescens (MIC 12.5-25 uM), S. flexneri (MIC 25-50 uM), E-coli (MIC >50 uM), V-harveyi (MIC >50 uM), Gram-positive M
Evidence 3 Activity

Activity

MIC
Antibacterial
25-50 µM

Target

S. flexneri

Source & Reference

dbAMP

Other

tive against Gram-negative A. hydrophila (MIC 30-60 uM), P. fluorescens (MIC 12.5-25 uM), S. flexneri (MIC 25-50 uM), E-coli (MIC >50 uM), V-harveyi (MIC >50 uM), Gram-positive M. luteus (MIC 6.25-12.5 uM),
Evidence 4 Activity

Activity

MIC
Antibacterial
6.25-12.5 µM

Target

M. luteus

Source & Reference

dbAMP

Other

), S. flexneri (MIC 25-50 uM), E-coli (MIC >50 uM), V-harveyi (MIC >50 uM), Gram-positive M. luteus (MIC 6.25-12.5 uM), S. aureus (MIC 6.25-12.5 uM), B. subtilis (MIC 25-50 uM), C. glutamicum (MIC 12.5-25 uM)
Evidence 5 Activity

Activity

MIC
Antibacterial
6.25-12.5 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

E-coli (MIC >50 uM), V-harveyi (MIC >50 uM), Gram-positive M. luteus (MIC 6.25-12.5 uM), S. aureus (MIC 6.25-12.5 uM), B. subtilis (MIC 25-50 uM), C. glutamicum (MIC 12.5-25 uM), B-cereus (MIC > 50 uM), and
Evidence 6 Activity

Activity

MIC
Antibacterial
25-50 µM

Target

B. subtilis

Source & Reference

dbAMP

Other

i (MIC >50 uM), Gram-positive M. luteus (MIC 6.25-12.5 uM), S. aureus (MIC 6.25-12.5 uM), B. subtilis (MIC 25-50 uM), C. glutamicum (MIC 12.5-25 uM), B-cereus (MIC > 50 uM), and S. epidermidis (MIC>50 uM),
Evidence 7 Activity

Activity

MIC
Antibacterial
12.5-25 µM

Target

C. glutamicum

Source & Reference

dbAMP

Other

e M. luteus (MIC 6.25-12.5 uM), S. aureus (MIC 6.25-12.5 uM), B. subtilis (MIC 25-50 uM), C. glutamicum (MIC 12.5-25 uM), B-cereus (MIC > 50 uM), and S. epidermidis (MIC>50 uM), Filamentous fungi A-niger (MIC >
Evidence 8 Activity

Activity

MIC
Antibacterial
>50 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP

Other

, B. subtilis (MIC 25-50 uM), C. glutamicum (MIC 12.5-25 uM), B-cereus (MIC > 50 uM), and S. epidermidis (MIC>50 uM), Filamentous fungi A-niger (MIC >50 uM), F-solani (MIC >50 uM), yeast C-candida (MIC>50 u
Evidence 9 Activity

Activity

MIC
Antifungal
30-60 µM

Target

A. hydrophila

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
binant protein, in vitro activity assays revealed that it is active against Gram-negative A. hydrophila (MIC 30-60 uM), P. fluorescens (MIC 12.5-25 uM), S. flexneri (MIC 25-50 uM), E-coli (MIC >50 uM), V-harv
Evidence 10 Activity

Activity

MIC
Antifungal
12.5-25 µM

Target

Pseudomonas fluorescens

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ity assays revealed that it is active against Gram-negative A. hydrophila (MIC 30-60 uM), P. fluorescens (MIC 12.5-25 uM), S. flexneri (MIC 25-50 uM), E-coli (MIC >50 uM), V-harveyi (MIC >50 uM), Gram-positive M
Evidence 11 Activity

Activity

MIC
Antifungal
25-50 µM

Target

S. flexneri

Source & Reference

dbAMP CAFPdb Antifungipept

Other

tive against Gram-negative A. hydrophila (MIC 30-60 uM), P. fluorescens (MIC 12.5-25 uM), S. flexneri (MIC 25-50 uM), E-coli (MIC >50 uM), V-harveyi (MIC >50 uM), Gram-positive M. luteus (MIC 6.25-12.5 uM),
Evidence 12 Activity

Activity

MIC
Antifungal
6.25-12.5 µM

Target

M. luteus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

), S. flexneri (MIC 25-50 uM), E-coli (MIC >50 uM), V-harveyi (MIC >50 uM), Gram-positive M. luteus (MIC 6.25-12.5 uM), S. aureus (MIC 6.25-12.5 uM), B. subtilis (MIC 25-50 uM), C. glutamicum (MIC 12.5-25 uM)
Evidence 13 Activity

Activity

MIC
Antifungal
6.25-12.5 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

E-coli (MIC >50 uM), V-harveyi (MIC >50 uM), Gram-positive M. luteus (MIC 6.25-12.5 uM), S. aureus (MIC 6.25-12.5 uM), B. subtilis (MIC 25-50 uM), C. glutamicum (MIC 12.5-25 uM), B-cereus (MIC > 50 uM), and
Evidence 14 Activity

Activity

MIC
Antifungal
25-50 µM

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

i (MIC >50 uM), Gram-positive M. luteus (MIC 6.25-12.5 uM), S. aureus (MIC 6.25-12.5 uM), B. subtilis (MIC 25-50 uM), C. glutamicum (MIC 12.5-25 uM), B-cereus (MIC > 50 uM), and S. epidermidis (MIC>50 uM),
Evidence 15 Activity

Activity

MIC
Antifungal
12.5-25 µM

Target

C. glutamicum

Source & Reference

dbAMP CAFPdb Antifungipept

Other

e M. luteus (MIC 6.25-12.5 uM), S. aureus (MIC 6.25-12.5 uM), B. subtilis (MIC 25-50 uM), C. glutamicum (MIC 12.5-25 uM), B-cereus (MIC > 50 uM), and S. epidermidis (MIC>50 uM), Filamentous fungi A-niger (MIC >
Evidence 16 Activity

Activity

MIC
Antifungal
>50 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

, B. subtilis (MIC 25-50 uM), C. glutamicum (MIC 12.5-25 uM), B-cereus (MIC > 50 uM), and S. epidermidis (MIC>50 uM), Filamentous fungi A-niger (MIC >50 uM), F-solani (MIC >50 uM), yeast C-candida (MIC>50 u