Peptide record

TPDB20568

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB20568
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GNWRKIVHKIKKAG
Physicochemical Analysis
C75H127N25O16
DCEQLMFPSTY
K
1634.99
11.80
6
0
5
+5
3.60
-0.964
83.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
336.39
1
Residue Composition
number
1
A
1
R
1
N
0
D
0
C
0
E
0
Q
2
G
1
H
2
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 2 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
14
C75H127N25O16
1634.99
11.80
+5
3.60
-0.964
Evidence Records 1 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
>2000 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | >2000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Machine learning designs non-hemolytic antimicrobial peptides. | Chem Sci | 2021