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Peptide record

TPDB20548

Antibacterial Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB20548
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GNNXPVYIPQPXPPHPXL
Physicochemical Analysis
C77H114N20O20
ARDCEKMFSTW
P
1639.87
7.77
1
0
4
+0
3.35
-0.694
59.44
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
90.86
4
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
1
Q
1
G
1
H
1
I
1
L
0
K
0
M
0
F
6
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 1 I: 1 L: 1 K: 0 M: 0 F: 0 P: 6 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
18
C77H114N20O20
1639.87
7.77
+0
3.35
-0.694
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
300 µM
Hemolytic Cytotoxic
0% Hemolysis | 300 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Substitution of the arginine/leucine residues in apidaecin Ib with peptoid residues: effect on antimicrobial activity, cellular uptake, and proteolytic degradation. | J Med Chem | 2009