Peptide record

TPDB20513

Antibacterial Antifungal Toxicity modified_plain modified
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB20513
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 12-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
GKXMSLLKHILK
Physicochemical Analysis
C58H106N16O13S1
ARNDCEQFPTWYV
LK
1267.64
10.84
4
0
5
+3
1.85
0.142
130.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
3
L
3
K
1
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 3 K: 3 M: 1 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C58H106N16O13S1
1267.64
10.84
+3
1.85
0.142
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
50% Hemolysis | 50 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Novel antimicrobial peptides from the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs. | Amino Acids | 2010