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Peptide record

TPDB20490

Antibacterial Toxicity modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB20490
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 10-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GLXKRXKTLL
Physicochemical Analysis
C42H81N13O10
ANDCEQHIMFPSWYV
L
928.19
11.64
3
0
3
+3
1.26
-0.200
117.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
3
L
2
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 3 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C42H81N13O10
928.19
11.64
+3
1.26
-0.200
Evidence Records 3 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
<5% Hemolysis | 256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Effect of N-methylated and fatty acid conjugation on analogs of antimicrobial peptide Anoplin | Eur J Pharm Sci | 2020
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
50% Hemolysis | 64 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Effect of N-methylated and fatty acid conjugation on analogs of antimicrobial peptide Anoplin | Eur J Pharm Sci | 2020
Evidence 3 Activity

Activity

40% Killing
Toxicity
16 µM
Cytotoxic
40% Killing | 16 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Effect of N-methylated and fatty acid conjugation on analogs of antimicrobial peptide Anoplin | Eur J Pharm Sci | 2020