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Peptide record

TPDB20487

Antibacterial Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB20487
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 29-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GLWTTIKEGVKNFSVGVLDKIRCKITGGC
Physicochemical Analysis
C139H232N38O39S2
AQHMPY
G
3123.72
9.71
5
2
10
+3
3.74
0.176
97.24
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5625
180.07
7
Residue Composition
number
0
A
1
R
1
N
1
D
2
C
1
E
0
Q
5
G
0
H
3
I
2
L
4
K
0
M
1
F
0
P
1
S
3
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 1 C: 2 E: 1 Q: 0 G: 5 H: 0 I: 3 L: 2 K: 4 M: 0 F: 1 P: 0 S: 1 T: 3 W: 1 Y: 0 V: 3
Chemical Descriptors
29
C139H232N38O39S2
3123.72
9.71
+3
3.74
0.176
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4-8 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

Active against E. coli ATCC 25922 (MIC 4-8 ug/ml), S. enteritidis (MIC 32 ug/ml), and S. aureus ATCC 29213 (MIC 16-32 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

S. enteritidis

Source & Reference

NA

Other

Active against E. coli ATCC 25922 (MIC 4-8 ug/ml), S. enteritidis (MIC 32 ug/ml), and S. aureus ATCC 29213 (MIC 16-32 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
16-32 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

Active against E. coli ATCC 25922 (MIC 4-8 ug/ml), S. enteritidis (MIC 32 ug/ml), and S. aureus ATCC 29213 (MIC 16-32 ug/ml).
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >128 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP