Peptide record

TPDB20457

Antibacterial Antifungal Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB20457
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GLWNSIKIA
Physicochemical Analysis
C47H76N12O12
RDCEQHMFPTYV
I
1001.19
10.10
1
0
5
+1
-1.65
0.567
141.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
549.34
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
1
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 1 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
9
C47H76N12O12
1001.19
10.10
+1
-1.65
0.567
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
512 µM
Hemolytic Cytotoxic
0% Hemolysis | 512 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Targeted Modification and Structure-Activity Study of GL-29, an Analogue of the Antimicrobial Peptide Palustrin-2ISb. | Antibiotics (Basel) | 2022
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Targeted Modification and Structure-Activity Study of GL-29, an Analogue of the Antimicrobial Peptide Palustrin-2ISb. | Antibiotics (Basel) | 2022