Peptide record

TPDB20410

Antibacterial Antiviral Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB20410
Antibacterial Antiviral Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Antiviral, Hemolysis, and other sources) peptide sequence curated from Peptipedia, AI4AVP, HemoPI, and other sources, with an available 3D structural model.
Sequence
GLPVCGETCVGGTCNTPGCTCSWPVCTKN
Physicochemical Analysis
C117H187N33O40S6
ARDQHIMFY
C
2888.33
5.90
1
1
5
-0
2.44
0.172
43.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
203.40
14
Residue Composition
number
0
A
0
R
2
N
0
D
6
C
1
E
0
Q
5
G
0
H
0
I
1
L
1
K
0
M
0
F
3
P
1
S
5
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 6 E: 1 Q: 0 G: 5 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 3 S: 1 T: 5 W: 1 Y: 0 V: 3
Chemical Descriptors
29
C117H187N33O40S6
2888.33
5.90
-0
2.44
0.172
Evidence Records 2 records
Evidence 1 Activity

Activity

12% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
12% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. | J Biol Chem | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis