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Peptide record

TPDB20395

Antibacterial Antiviral Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB20395
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia and AI4AVP, with an available 3D structural model.
Sequence
GLPVCGDTCVGGTCNTPGCTCSWPVCTRN
Physicochemical Analysis
C116H185N35O40S6
AEQHIKMFY
C
2902.32
5.71
1
1
5
-0
1.47
0.152
43.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
202.42
14
Residue Composition
number
0
A
1
R
2
N
1
D
6
C
0
E
0
Q
5
G
0
H
0
I
1
L
0
K
0
M
0
F
3
P
1
S
5
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 1 C: 6 E: 0 Q: 0 G: 5 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 3 S: 1 T: 5 W: 1 Y: 0 V: 3
Chemical Descriptors
29
C116H185N35O40S6
2902.32
5.71
-0
1.47
0.152
Evidence Records 1 records
Evidence 1 Activity

Activity

4% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
4% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. | J Biol Chem | 2011