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Peptide record

TPDB20378

Antibacterial Antiviral Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB20378
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP AVPpred-BWR dbAMP 3.0 DRAVP 2.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, AVPpred-BWR, and other sources, with an available 3D structural model.
Sequence
GLLSVLGSVAKHVLPHVVPVIAKLH
Physicochemical Analysis
C122H207N33O28
RNDCEQMFTWY
V
2584.19
10.60
5
0
14
+2
3.01
1.172
171.20
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
3
H
1
I
5
L
2
K
0
M
0
F
2
P
2
S
0
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 3 I: 1 L: 5 K: 2 M: 0 F: 0 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 6
Chemical Descriptors
25
C122H207N33O28
2584.19
10.60
+2
3.01
1.172
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
17 µM
Cytotoxic
50% Cell death | 17 | µM | target cell: CD4+ T Lymphocytes

Target

CD4+ T Lymphocytes

Source & Reference

NA
DBAASP
Inhibition of HIV Infection by Caerin 1 Antimicrobial Peptides | Peptides | 2015
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.26026377]CD4+ T Lymphocytes:50% cell death at 17 µM.

Source & Reference

NA
DRAMP
Peptides. 2015 Sep 71:296-303.