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Peptide record

TPDB20360

Antibacterial Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB20360
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 30-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GLLLDTVKGAAKNVAGILLNKLKCKVTGDC
Physicochemical Analysis
C134H239N37O39S2
REQHMFPSWY
L
3056.72
9.65
5
2
13
+3
4.12
0.460
130.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.09
6
Residue Composition
number
3
A
0
R
2
N
2
D
2
C
0
E
0
Q
4
G
0
H
1
I
6
L
5
K
0
M
0
F
0
P
0
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 2 C: 2 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 6 K: 5 M: 0 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
30
C134H239N37O39S2
3056.72
9.65
+3
4.12
0.460
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64-128 ug/ml), and S. aureus ATCC 29213 (MIC 16-32 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
64-128 µg/mL

Target

S. enteritidis

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64-128 ug/ml), and S. aureus ATCC 29213 (MIC 16-32 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
16-32 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64-128 ug/ml), and S. aureus ATCC 29213 (MIC 16-32 ug/ml).
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >128 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP