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Peptide record

TPDB20336

Antibacterial Anticancer Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB20336
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GLLGKILGAGKKVL
Physicochemical Analysis
C64H119N17O15
RNDCEQHMFPSTWY
GL
1366.75
10.84
3
0
7
+3
0.36
0.886
167.14
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
1
I
4
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 4 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
14
C64H119N17O15
1366.75
10.84
+3
0.36
0.886
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
700 µM
Hemolytic Cytotoxic
0% Hemolysis | 700 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
A novel antimicrobial peptide found in Pelophylax nigromaculatus | J Genet Eng Biotechnol | 2022
Evidence 2 Activity

Activity

LC50
Toxicity
>100 µM
Cytotoxic
LC50 | >100 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
A novel antimicrobial peptide found in Pelophylax nigromaculatus | J Genet Eng Biotechnol | 2022
Evidence 3 Activity

Activity

LC50
Toxicity
>100 µM
Cytotoxic
LC50 | >100 | µM | target cell: Human microvascular endothelial cells HMEC-1

Target

Human microvascular endothelial cells HMEC-1

Source & Reference

NA
DBAASP
A novel antimicrobial peptide found in Pelophylax nigromaculatus | J Genet Eng Biotechnol | 2022