Back to search

Peptide record

TPDB20331

N-E5L-Sc18 Antibacterial Anticancer Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB20331
N-E5L-Sc18
Antibacterial Anticancer Cell-penetrating Peptides
Anti-infective peptides Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 PerseuCPP
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, and Cell-penetrating Peptides) peptide sequence curated from Peptipedia, CellPPD, CellPPD-MOD, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
GLLEALAELLEGLRKRLRKFRNKIKEK-NH2
Physicochemical Analysis
C145H257N45O37
DCQHMPSTWYV
L
3222.91
11.04
9
4
11
+5
11.01
-0.678
122.96
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
4
R
1
N
0
D
0
C
4
E
0
Q
2
G
0
H
1
I
7
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 1 D: 0 C: 0 E: 4 Q: 0 G: 2 H: 0 I: 1 L: 7 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
27
C145H257N45O37
3222.91
11.04
+5
11.01
-0.678
Amidation
L
Linear
Conjugation with fluorescein
NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, HEK 293 and MCF-8

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Fluorophore (fluorescein)
Cytosol and nucleus
Endocytic pathway
In vitro
CCSHHHHHHHHHHHHHHHTTTTTTTCC
Additional Detail Fields 1 fields
CCSHHHHHHHHHHHHHHHTTTTTTTCC